Putative acyl-CoA dehydrogenase AidB (IPR034184)

Short name: AidB

Overlapping homologous superfamilies

Family relationships



AidB is one of several genes involved in the SOS adaptive response to DNA alkylation damage, whose expression is activated by the Ada protein [PMID: 3278898, PMID: 12220590]. Its function has not been entirely elucidated; however, it is similar in sequence and function to acyl-CoA dehydrogenases [PMID: 9732461, PMID: 25981666]. It has been proposed that aidB directly destroys DNA alkylating agents such as nitrosoguanidines (nitrosated amides) or their reaction intermediates [PMID: 12483506, PMID: 18829440].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.