Ecto-NOX disulfide-thiol exchanger, RNA recognition motif (IPR034140)

Short name: ENOX_RRM

Overlapping homologous superfamilies

Domain relationships


This entry represents the conserved RNA recognition motif (RRM) in ECTO-NOX proteins (ENOX).

ENOX proteins are growth-related cell surface proteins that catalyse both hydroquinone or NADH oxidation and protein disulfide-thiol interchange [PMID: 19055324]. The two enzymatic activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock [PMID: 19055324, PMID: 20922471]. ENOX proteins may play roles in cancer, cellular time-keeping, growth, aging and neurodegenerative diseases [PMID: 14567438].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.