Pathways & interactions
Ecto-NOX disulfide-thiol exchanger, RNA recognition motif (IPR034140)
Short name: ENOX_RRM
Overlapping homologous superfamilies
- Nucleotide-binding alpha-beta plait domain superfamily (IPR012677)
- RNA-binding domain superfamily (IPR035979)
- RNA recognition motif domain (IPR000504)
- Ecto-NOX disulfide-thiol exchanger, RNA recognition motif (IPR034140)
This entry represents the conserved RNA recognition motif (RRM) in ECTO-NOX proteins (ENOX).
ENOX proteins are growth-related cell surface proteins that catalyse both hydroquinone or NADH oxidation and protein disulfide-thiol interchange [PMID: 19055324]. The two enzymatic activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock [PMID: 19055324, PMID: 20922471]. ENOX proteins may play roles in cancer, cellular time-keeping, growth, aging and neurodegenerative diseases [PMID: 14567438].
- cd12228 (RRM_ENOX)