Fungal reprolysin domain (IPR034028)

Short name: ZnMc_ADAM_fungal

Overlapping homologous superfamilies

Domain relationships


The ADAM (A Disintegrin And Metalloprotease) family of metalloproteases are integral membrane proteases acting on a variety of extracellular targets. They are involved in shedding soluble peptides or proteins from the cell surface [PMID: 15936900]. This entry contains fungal ADAMs, whose precise function has yet to be determined, including PCADAM from Pneumocystis (MEROPS identifier M12.336) [PMID: 19451239] and MDE10 from Schizosaccharomyces (MEROPS identifier M12.180) [PMID: 14871934].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.