Domain

ADAM10/ADAM17 catalytic domain (IPR034025)

Short name: ADAM10_ADAM17

Overlapping homologous superfamilies

Domain relationships

Description

This entry includes proteins with reprolysin-like metallopeptidase domains and includes ADAM10 (also known as myelin-associated metalloendopeptidase, MEROPS identifier M12.210), ADAM17 (also known as tumour necrosis factor alpha-convertase, MEROPS identifier M12.217), kuzbanian (MEROPS identifiers M12.211 and M12.322) and ADM-4 (MEROPS identifier M12.329) [PMID: 10415747].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008237 metallopeptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD