Domain

Endolysin/autolysin (IPR033907)

Short name: Endolysin_autolysin

Overlapping homologous superfamilies

Domain relationships

None.

Description

Endolysins and autolysins are found in viruses and bacteria, respectively [PMID: 8564539]. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls [PMID: 8765293]. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall hetropolymer peptidoglycan and cell division [PMID: 8765294]. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.

This entry represents the lysozyme domain found in endolysins, autolysins and lysozymes.

GO terms

Biological Process

GO:0044659 cytolysis by virus of host cell

Molecular Function

GO:0003796 lysozyme activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD