MADS MEF2-like (IPR033896)

Short name: MADS_MEF2-like

Overlapping homologous superfamilies

Domain relationships


This entry represents the MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor)) box family of eukaryotic transcriptional regulators [PMID: 7744019]. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface [PMID: 10835359]. Important in homeotic regulation in plants and in immediate-early development in animals [PMID: 10805792]. Also found in fungi [PMID: 8875863].

GO terms

Biological Process

GO:0045944 positive regulation of transcription by RNA polymerase II

Molecular Function

GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.