DNA damage inducible protein 1 ubiquitin-like domain (IPR033882)

Short name: DDI1_N

Overlapping homologous superfamilies

Domain relationships

  • Ubiquitin domain (IPR000626)
    • DNA damage inducible protein 1 ubiquitin-like domain (IPR033882)


DDI1 (DNA damage inducible protein 1) has an amino-terminal ubiquitin-like domain, an retroviral protease-like (RVP-like) domain, and a UBA (ubiquitin-associated) domain. This entry represents the amino-terminal ubiquitin-like domain of DDI1 [PMID: 11700052,PMID: 11323716,PMID: 11713673].

Ubiquitin is a globular protein, the last four C-terminal residues (Leu-Arg-Gly-Gly) extending from the compact structure to form a 'tail', important for its function. The latter is mediated by the covalent conjugation of ubiquitin to target proteins, by an isopeptide linkage between the C-terminal glycine and the epsilon amino group of lysine residues in the target proteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.