Glycogen synthase kinase-3 beta (IPR033573)

Short name: GSK3B

Overlapping homologous superfamilies

Family relationships



GSK3B is a serine/threonine kinase that regulates many biological processes such as muscle differentiation [PMID: 26785133], tau-microtubule interactions [PMID: 14690523], Wnt signalling [PMID: 15647282] and epithelial-mesenchymal transition during embryonic development [PMID: 15448698]. It has been implicated in various diseases such as diabetes, inflammation, cancer, Alzheimer's and bipolar disorder [PMID: 19366350].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004672 protein kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.