Family

Thy-1 membrane glycoprotein (IPR033292)

Short name: THY1

Family relationships

None.

Description

Thy-1 membrane glycoprotein (also known as CD90) was identified as an activation-associated cell adhesion molecule on human dermal microvascular endothelial cells. Its cellular effects vary; however, it most often seems to affect cell-cell or cell-matrix interactions and cellular adhesion and migration [PMID: 15093746, PMID: 25300130]. Thy-1 interacts with the leukocyte integrin Mac-1 and may play an important role in the regulation of leukocyte recruitment to sites of inflammation [PMID: 15004192]. It also plays an important role in normal retinal development [PMID: 10567740].

GO terms

Biological Process

GO:0007155 cell adhesion
GO:0030334 regulation of cell migration

Molecular Function

GO:0005178 integrin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER