Family

GON-4-like protein (IPR033277)

Short name: GON-4-like

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

GON-4-like has transcriptional repressor activity, probably as part of a complex with the DNA-binding protein YY1, the co-repressor Sin3a, and the histone-modifying enzyme histone deacetylase 1 (HDAC1) [PMID: 21454521]. GON-4-like is essential for B lymphopoiesis and may function to regulate gene expression during this process [PMID: 20530203].

GO terms

Biological Process

GO:0030183 B cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

GO:0003714 transcription corepressor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER