Family

Calcium-binding protein 4 (IPR033014)

Short name: CABP4

Overlapping homologous superfamilies

Family relationships

None.

Description

Calcium-binding protein 4 (CABP4) can be found in retina and in the inner hair cells (IHC) of the cochlea [PMID: 16249514, PMID: 17947313]. In retina CABP4 is essential for the development and maintenance of the mouse photoreceptor synapse [PMID: 16249514]. It controls the continuous release of the glutamate neurotransmitter in dark state photoreceptor cells [PMID: 22393316] by regulating L-type calcium channels (Cav1.4) [PMID: 15452577, PMID: 22936811, PMID: 25258313]. In IHC it acts as an integral subunit and modulator of Cav channels [PMID: 17947313].

GO terms

Biological Process

GO:0007165 signal transduction
GO:0007601 visual perception

Molecular Function

GO:0005246 calcium channel regulator activity
GO:0005509 calcium ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER