Family

Retinaldehyde-binding protein 1 (IPR032941)

Short name: RLBP1

Overlapping homologous superfamilies

Family relationships

None.

Description

Retinaldehyde-binding protein 1 (RLBP1, also known as CRALBP) is a retinoid-binding protein expressed in retinal pigment epithelial and Müller glia and is believed to be involved in the retinal visual cycle [PMID: 25607845]. It is essential for mammalian vision by routing 11-cis-retinoids for the conversion of photobleached opsin molecules into photosensitive visual pigments [PMID: 19846785]. Mutations in the RLBP1 gene cause retinitis pigmentosa autosomal recessive (ARRP) [PMID: 9326942] and Bothnia retinal dystrophy (BRD) [PMID: 11868161].

GO terms

Biological Process

GO:0007601 visual perception

Molecular Function

GO:0016918 retinal binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER