Brain mitochondrial carrier protein 1 (IPR032933)
Short name: SLC25A14
Overlapping homologous superfamilies
- Mitochondrial carrier domain superfamily (IPR023395)
- Mitochondrial carrier UCP-like (IPR002030)
- Brain mitochondrial carrier protein 1 (IPR032933)
Brain mitochondrial carrier protein 1 (SLC25A14, also known as UCP5) is a member of the SLC25 family. UCP5 may be involved in tissue-specific thermoregulation and metabolic changes associated with nutritional status [PMID: 10928996]. Overexpression of UCP5 resulted in reduced mitochondrial membrane potential (MMP), reduced intracellular ATP content, and reduced levels of ROS [PMID: 22950050].
Mitochondrial solute carrier 25 (SLC25) family proteins function as transporters of a large variety of molecules, including ATP, ADP and amino acids [PMID: 22950050].
- PTHR24089:SF299 (PTHR24089:SF299)