Domain

Resistance to inhibitors of cholinesterase protein 3, N-terminal (IPR032763)

Short name: RIC3_N

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the N-terminal domain of RIC3, a protein associated with nicotinic acetylcholine receptors (nAChRs), neurotransmitter-gated ion channels expressed at the neuromuscular junction and within the central and peripheral nervous systems [PMID: 11867529, PMID: 12821669]. It can enhance functional expression of multiple nAChR subtypes [PMID: 16120769]. RIC3 promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface [PMID: 15809299].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam