Family

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (IPR032748)

Short name: PAG

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

PAG, or Cbp/PAG (Csk binding protein/phospho-protein associated with glycosphingolipid-enriched microdomains) is a transmembrane protein that has a negative regulatory role in T-cell activation through being an adapter for C-terminal Src kinase, Csk. This family of proteins is found in eukaryotes [PMID: 10790433, PMID: 11684085, PMID: 12612075, PMID: 22659621].

GO terms

Biological Process

GO:0035556 intracellular signal transduction
GO:0050868 negative regulation of T cell activation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0045121 membrane raft
GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam