Domain

Plasminogen-binding protein PgbA, C-terminal (IPR032737)

Short name: PGBA_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the C-terminal domain of bacterial proteins that bind plasminogen (PgbA and PgbB). This activity was identified in Helicobacter pylori where it is thought to contribute to the virulence of this bacterium. Both PgbA and PgbB are surface-exposed proteins that mediate binding to plasminogen such that it can be converted into plasmin in the presence of a plasminogen activator [PMID: 14769936].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam