Domain

Protein SirB1, N-terminal (IPR032698)

Short name: SirB1_N

Domain relationships

None.

Description

This domain can be found in the N terminus of the bacterial SirB1 protein. It can also be found in the mammalian F-box only protein 21 (FBXO21).

SirB is required for maximal expression of sirC, which encodes an SPI1-encoded transcription factor [PMID: 10322010].

FBXO21 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex [PMID: 26085330].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam