Family

Neurogenin-1 (IPR032653)

Short name: Ngn1

Family relationships

None.

Description

Neurogenin-1 (Ngn1, also known as neuroD3) is a basic helix-loop-helix transcription factor that is involved in neurogenesis [PMID: 18007592]. It interacts with other transcriptional regulators, such as Sox2, during neurogenesis [PMID: 23447599].

The bHLH (basic Helix-Loop-Helix) proteins contain the bHLH domain that is approximately 60 amino acids long and consists of a DNA-binding basic region followed by two a-helices separated by a variable loop region (HLH). The HLH domain promotes dimerisation, allowing the formation of homo- or heterodimeric complexes between different family members. Many bHLH proteins have been shown to act as transcriptional regulators [PMID: 12806077].

GO terms

Biological Process

GO:0022008 neurogenesis
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER