Family

Neurogenic differentiation factor 1 (IPR032652)

Short name: Neurod1

Family relationships

Description

Neurogenic differentiation factor 1 (Neurod1) is a basic helix-loop-helix (bHLH) transcription factor that is involved in neurogenesis [PMID: 18007592]. It has been found overexpressed in a variety of aggressive neural/neuroendocrine carcinomas [PMID: 23553831].

The bHLH (basic Helix-Loop-Helix) proteins contain the bHLH domain that is approximately 60 amino acids long and consists of a DNA-binding basic region followed by two a-helices separated by a variable loop region (HLH). The HLH domain promotes dimerisation, allowing the formation of homo- or heterodimeric complexes between different family members. Many bHLH proteins have been shown to act as transcriptional regulators [PMID: 12806077].

GO terms

Biological Process

GO:0048666 neuron development
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER