Domain

Mon2, dimerisation and cyclophilin-binding domain (IPR032629)

Short name: DCB_dom

Domain relationships

None.

Description

This is the N-terminal domain of Mon2- and BIG1-like proteins. The N terminus of Mon2 (Ysl2) binds to Arf-Like small GTPase Arl1, and shows homology to brefeldin A-inhibited guanine-exchange factor (BIG) domains [PMID: 12052896]. Mon2 and BIG1-like proteins play an important role in membrane traffic and Golgi homeostasis [PMID: 16219684, PMID: 16301316, PMID: 18417613].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam