Domain

DAMP1, SANT/Myb-like domain (IPR032563)

Short name: DAMP1_SANT-like

Overlapping homologous superfamilies

None.

Domain relationships

Description

This domain, approximately 90 residues, is mainly found in DNA methyltransferase 1-associated protein 1 (DAMP1), which plays an important role in development and maintenance of genome integrity in various mammalian species [PMID: 19845771, PMID: 21383065]. It mainly consists of tandem repeats of three alpha-helices that are arranged in a helix-turn-helix motif and shows a structural similarity with SANT domain and Myb DNA-binding domain, indicating it contains a putative DNA-binding site [PMID: 8882580].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam