Domain

GAIN domain, N-terminal (IPR032471)

Short name: GAIN_dom_N

Domain relationships

None.

Description

This entry represents the N-terminal region of the GAIN domain. The full GAIN domain, comprises this domain and the GPS motif (IPR000203), can be found in cell-adhesion GPCRs, and is the functional unit for autoproteolysis. The GPS motif is an ancient domain that exists in primitive ancestor organisms, and the full GAIN domain is conserved in all cell-adhesion GPCRs and all PKD1-related proteins [PMID: 22333914].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam