Family

Phosphatidate phosphatase PPAPDC1B (IPR032462)

Short name: PPAPDC1B

Overlapping homologous superfamilies

Family relationships

None.

Description

PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) are novel mammalian phosphatidate phosphatases that show greater homology to yeast diacylglycerol pyrophosphate phosphatase DPP1 than to known phosphatidate phosphatases of mammals [PMID: 17590538]. These enzymes catalyse the conversion of phosphatidic acid to diacylglycerol and display magnesium-independent phosphatidate phosphatase activity in vitro.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER