Domain

CAAX prenyl protease 1, N-terminal (IPR032456)

Short name: Peptidase_M48_N

Domain relationships

None.

Description

This entry represents the N-terminal five transmembrane alpha-helices domain of CAAX prenyl protease 1 (also known as Ste24 in budding yeast). Ste24 is a zinc metalloprotease catalysing two proteolytic steps in the maturation of yeast mating pheromone a-factor [PMID: 23539602]. The structures of Ste24 and its human homologue, ZMPSTE24, have been revealed [PMID: 23539602, PMID: 23539603].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam