Domain

Rho guanine nucleotide exchange factor, coiled-coil domain (IPR032409)

Short name: GEF_CC

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents a C-terminal coiled-coil region found in a group of Rho guanine nucleotide exchange factors (GEFs), including betaPIX [PMID: 20117114]. This domain is upstream of the PDZ binding motif and is important for the multimerization of betaPIX [PMID: 20117114].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam