Domain

Cyclic nucleotide-gated channel, C-terminal leucine zipper domain (IPR032406)

Short name: CLZ_dom

Domain relationships

None.

Description

This entry represents the C-terminal leucine-zipper domain (also known as CLZ domain) of of cyclic nucleotide-gated channel proteins. This domain forms homotypic trimers in solution thus constraining the channel of the CNGs to contain three cyclic nucleotide-gated subunits, CNGA. The CLZ domains formed homotypic parallel 3-helix coiled-coil domains, consistent with their proposed role in regulating subunit assembly [PMID: 21878911].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam