Domain

Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (IPR032353)

Short name: AZUL

Domain relationships

None.

Description

The AZUL or amino-terminal zinc-binding domain of ubiquitin E3a ligase (Ube3A) is found in eukaryotes, and is an unusual zinc-finger domain. The final cysteine is usually mutated in Angelman syndrome patients. It is likely that AZUL plays a role in Ube3A substrate-recognition [PMID: 21947926].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam