Domain

Methyl-CpG-binding domain protein 2/3, p55-binding region (IPR032343)

Short name: MBD2/MBD3_p55-bd

Domain relationships

None.

Description

This entry represents a second MBD domain of methyl-CpG-binding domain proteins 2 and 3. This region has been implicated in binding the RbAp46/48 (retinoblastoma protein-associated protein) homologue p55, which is one of the components of the MBD2-NuRD complex. The MBD2-NuRD complex is a nucleosome remodelling and deacetylation complex [PMID: 21490301].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam