Family

RecQ-mediated genome instability protein 2 (IPR032245)

Short name: RMI2

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The dissolvasome is a protein complex that consists of BLM, a RecQ helicase that is product of the gene mutated in Bloom syndrome, topoisomerase IIIalpha (Top3alpha) and the RMI (RecQ-mediated genome instability) subcomplex, comprised of RMI1 and RMI2. The dissolvasome acts on double Holliday junction intermediates in homologous recombination, creating non-crossover products in a process termed 'dissolution' [PMID: 14685245, PMID: 16537486].

RMI2 is an OB3, oligo-nucleotide-binding protein. It is an essential component of the RMI complex [PMID: 20826341].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER