Domain

C-terminal of Roc (COR) domain (IPR032171)

Short name: COR

Domain relationships

None.

Description

The C-terminal of Roc domain, or COR domain, functions along with Roc as a putative regulator of kinase activity. It functions as a proper GTP-binding protein with a low GTPase activity somehow stimulating the kinase activity [PMID: 18650931]. The Roc-COR tandem is found in bacterial and eukaryotic proteins. Its most prominent member is the leucine-rich repeat kinase LRRK2 [PMID: 18230735].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam