Domain

Telomeric repeat-binding factor 2, Rap1-binding domain (IPR031902)

Short name: TERF2_RBM

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This domain, found in mammalian telomeric repeat-binding factor 2 (TERF2, also known as TRF2) and fission yeast Taz1, binds to the C terminus of repressor activator protein 1 (RAP1) (telomeric repeat-binding factor 2-interacting protein 1) [PMID: 21217703]. Through this interaction, RAP1 is targeted to chromosome ends for telomere protection [PMID: 21217703].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
Pfam