PDZK1-interacting protein 1/SMIM24 (IPR031627)

Short name: PDZK1IP1/SMIM24

Family relationships


PDZK1-interacting protein 1 (PDZK1IP1, MAP17) is a small non-glycosylated two-pass membrane protein that is overexpressed in many tumours of different origins, including carcinomas [PMID: 8701988, PMID: 9461128, PMID: 12812916, PMID: 22465409].

This entry also includes small integral membrane protein 24 (SMIM24) from mammals and proximal tubules-expressed gene protein (pteg) from Xenopus. The function of SMIM24 is not clear. Pteg is essential for pronephric mesoderm specification and tubulogenesis [PMID: 19909807].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.