Family

Coiled-coil domain-containing protein 106 (IPR031591)

Short name: CCDC106

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

CCDC106, coiled-coil domain-containing protein 106, is a family of eukaryote proteins. Yeast two-hybrid screening has identified CCDC106 as a p53-interacting partner [PMID: 16169070]. CCDC106 is a negative regulator of p53 and may be involved in tumourigenesis in some cancers by promoting the degradation of p53 protein and inhibiting its transactivity [PMID: 20159018].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam