Domain

Sir4, SID domain (IPR031556)

Short name: SIR4_SID

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This is the Sir2 interaction domain (SID domain) of silent information regulator 4 (Sir4) [PMID: 23307867]. Sir4 is a silent information regulator (SIR) required for transcriptional repression of the silent mating type loci, HML and HMR. It also and helps maintain a repressed chromatin structure near telomeres [PMID: 18039933].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
Pfam