Family

RBPJ-interacting and tubulin-associated protein 1 (IPR031418)

Short name: RITA1

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

RITA (RBPJ-interacting and tubulin-associated protein) is a highly conserved protein that binds to tubulin and shuttles between the cytoplasm and nucleus. It is responsible for export of RBP-J/CBF-1 from the nucleus, which modulates Notch-mediated transcription [PMID: 21102556].

GO terms

Biological Process

GO:0007219 Notch signaling pathway
GO:0051168 nuclear export

Molecular Function

GO:0015631 tubulin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam