Family

Orofacial cleft 1 candidate gene 1 protein (IPR031390)

Short name: OFCC1

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family of proteins is found in eukaryotes. Proteins in this family are typically between 125 and 276 amino acids in length. The family includes OFCC1 (orofacial cleft 1 candidate gene 1 protein), a potentially causal gene for orofacial cleft in humans [PMID: 15218257]. However, ablation of the gene had no effects in head development in mice [PMID: 22242126]. Mutations in the homologous Opo gene result in eye malformation in medaka fish [PMID: 19502481].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam