Cellular retinoic acid-binding protein 1 (IPR031279)

Short name: CRABP1

Overlapping homologous superfamilies

Family relationships


The lipid-binding protein (LBP) family can be divided divided in four subfamiles. Subfamily I comprises proteins specific for vitamin A derivatives, and can be subdivided into the cellular retinoic acid-binding proteins (CRABP-I and II) and the cellular retinol-binding proteins (CRBP-I, II, III, and IV) [PMID: 15234551].

This entry represents retinoic acid-binding protein 1 (CRABP-I). Upon binding retinoic acid (RA), CRABP I participates in RA catabolism by producing its inactive metabolites [PMID: 1328234].

GO terms

Biological Process

GO:0034653 retinoic acid catabolic process

Molecular Function

GO:0001972 retinoic acid binding

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.