Fatty acid-binding protein, intestinal (IPR031272)

Short name: FABP2

Overlapping homologous superfamilies

Family relationships


Fatty acid-binding proteins (FABPs) have been designated according to the first tissue they were isolated from: intestinal (I-FABP), liver (L-FABP), adipocyte(A-FABP), heart (H-FABP), ileal, myelin, brain, epidermal, and sperm. However, each of these FABPs may be expressed in more than one tissue.

Intestinal fatty acid binding protein FABP2 (also known as IFABP) is expressed in intestinal enterocytes of mammals [PMID: 25458898]. IFABP may be involved with uptake of fatty acid from the lumen of the intestine, and with trafficking within the intestinal enterocyte to organelles [PMID: 25458898]. It may function as a lipid-sensing component of energy homeostasis that alters body weight gain in a gender-specific fashion [PMID: 11023988].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005504 fatty acid binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.