Calcipressin-1 (IPR031271)

Short name: RCAN1

Family relationships


Calcipressin-1 (RCAN1, also known as DSCR1) is a calcineurin inhibitor that inactivates nuclear factor of activated T cells (NFATc) activity [PMID: 17693409]. It is expressed in the primitive ventricle of the heart and during neurogenesis [PMID: 11231093]. The DSCR1 (Down syndrome critical region 1) gene is present in the region of human chromosome 21, trisomy of which is associated with congenital heart defects observed in Down syndrome [PMID: 14738882].

GO terms

Biological Process

GO:0033173 calcineurin-NFAT signaling cascade

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.