ATP-binding cassette sub-family D member 1 (IPR031237)

Short name: ALDP

Overlapping homologous superfamilies


Family relationships


ATP-binding cassette sub-family D member 1 (ABCD1) is a an ATP-binding-cassette (ABC) transporter located in the peroxisomal membrane. Its nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity [PMID: 11248239]. Mutations in the ABCD1 gene cause X-linked adrenoleukodystrophy (X-ALD), a disorder of peroxisomal fatty acid beta oxidation which results in the accumulation of very-long chain fatty acids in tissues throughout the body [PMID: 22483867].

GO terms

Biological Process

GO:0006635 fatty acid beta-oxidation

Molecular Function

GO:0005524 ATP binding
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0005778 peroxisomal membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.