AH receptor-interacting protein (IPR031208)

Short name: AIP

Family relationships



Arylhydrocarbon (AH) receptor-interacting protein (AIP) is a tetratricopeptide repeat (TPR)-containing protein that interacts with a large number of independent proteins as well as three chaperone systems, HSP90, HSP70 and TOMM20 [PMID: 23300914, PMID: 14557246]. Germline mutations in the AIP gene predispose to young-onset pituitary tumours, most often to GH- or prolactin-secreting adenomas, and most of these patients belong to familial isolated pituitary adenoma families [PMID: 21454441]. The structure of AIP has been revealed [PMID: 23300914].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.