Family

Na(+)/H(+) exchange regulatory cofactor NHERF-1 (IPR031199)

Short name: NHERF-1

Family relationships

Description

Na(+)/H(+) exchange regulatory cofactor NHERF-1 is a PDZ domain-containing protein that functions as a scaffolding protein. NHERF-1 interacts with the glutamate transporter GLAST during ER export [PMID: 23200831]. It has been shown to bind to the scavenger receptor megalin [PMID: 21325834]. NHERF-1 is likely to participate in channel functions associated with nociception and mechanosensation [PMID: 16234233].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0032947 protein complex scaffold activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER