Family

Na(+)/H(+) exchange regulatory cofactor NHERF-2 (IPR031197)

Short name: NHERF-2

Family relationships

Description

Na(+)/H(+) exchange regulatory cofactor NHERF-2 is a PDZ domain-containing protein that functions as a scaffolding protein for the glutamate transporter GLAST. It interacts with GLAST in the secretory pathway from the ER-Golgi intermediate compartment to the plasma membrane, thereby modulating the cell surface expression of GLAST [PMID: 23200831, PMID: 9096337].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0032947 protein complex scaffold activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER