Syndecan-1 (IPR031190)

Short name: Syndecan-1

Overlapping homologous superfamilies


Family relationships

  • Syndecan (IPR001050)
    • Syndecan-1 (IPR031190)


Four members of the syndecan family of transmembrane heparan sulfate proteoglycans are expressed in mammals, Sdc1-4 [PMID: 1335744, PMID: 21062643]. Syndecan 1 (Sdc1) plays an important role in regulating key events during wound healing, including cell adhesion, cell migration and fibrosis [PMID: 25945286, PMID: 20580707, PMID: 12200974]. Sdc1 is expressed in injured primary sensory neurons and may have a role in nerve regeneration and synaptic plasticity [PMID: 26002314].

GO terms

Biological Process

GO:0042060 wound healing

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.