Pathways & interactions
Crustacean CHH/MIH/GIH neurohormone family (IPR031098)
Short name: Crust_neurohorm
Overlapping homologous superfamilies
- Crustacean CHH/MIH/GIH neurohormone superfamily (IPR035957)
- Crustacean CHH/MIH/GIH neurohormone family (IPR031098)
- Hyperglycemic hormone (IPR001166)
Arthropod express a family of neuropeptides [PMID: 8590372] which so far consist of the following types of neurohormones:
- Crustacean hyperglycemic hormone (CHH). CHH is primarily involved in blood sugar regulation, but also plays a role in the control of molting and reproduction.
- Molt-inhibiting hormone (MIH). MIH inhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops.
- Gonad-inhibiting hormone (GIH), also known as vitellogenesis-inhibiting hormone (VIH) because of its role in inhibiting vitellogenesis in female animals.
- Mandibular organ-inhibiting hormone (MOIH). MOIH represses the synthesis of methyl farnesoate, the precursor of insect juvenile hormone III in the mandibular organ.
- Ion transport peptide (ITP) from locust. ITP stimulates salt and water reabsorption and inhibits acid secretion in the ileum of the locust.
Alpha-latrotoxin associated low molecular weight proteins (LMWPs) are a family of uncharacterised venom peptides associated with alpha-latrotoxin, a black widow spider neurotoxin, which are probably also expressed in the venoms of other Latrodectus and Steatoda species [PMID: 1509496, PMID: 7601118, PMID: 24316130].
This entry also includes proteins from Nematoda, such as Caenorhabditis elegans hypothetical protein ZC168.2.
- PF01147 (Crust_neurohorm)