Somatic embryogenesis receptor kinase (IPR031048)

Short name: SERK

Overlapping homologous superfamilies


Family relationships



The SERK (somatic embryogenesis receptor kinase) family is involved in a wide spectrum of biological processes, including plant development and disease resistance [PMID: 27449136]. SERKs (SERK1-5) are classified as subgroup II receptor-like kinases (RLKs). SERKs exist as coreceptors of multiple cell surface-receptors perceiving diverse stimuli via ligand-induced heterodimerization and transphosphorylation [PMID: 27660030]. They are involved in at least five different signalling pathways [PMID: 18667726].

Arabidopsis SERK1 and SERK2 are functionally redundant and essential for tapetum specification and pollen development during male sporogenesis [PMID: 16284305]. SERK3, also known as BAK1 (BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1), is the coreceptor of the brassinolide (BR)-perceiving receptor BRI1, a function that is BR dependent and partially redundant with SERK1 [PMID: 18667726]. SERK3 controls plant innate immunity and serves as a coreceptor of the flagellin receptor FLS2 [PMID: 17626179]. SERK4 is also involved in innate immunity [PMID: 21693696]. SERK3 and SERK4 are partially redundant in pathogen-induced cell death control [PMID: 18667726]. SERK5 contains a mutation in an important amino acid residue which likely abolishes the kinase activity of SERK [PMID: 22253607].

GO terms

Biological Process

GO:0007165 signal transduction

Molecular Function

GO:0004672 protein kinase activity
GO:0005102 signaling receptor binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.