Protein sprouty homologue 3 (IPR030786)

Short name: SPRY3

Overlapping homologous superfamilies


Family relationships

  • Sprouty (IPR007875)
    • Protein sprouty homologue 3 (IPR030786)


Protein sprouty homologue 3 (SPRY3) belongs to the sprouty family, whose members are inhibitors of the Ras-ERK pathway downstream of various receptor tyrosine kinases. SPRY3 plays an important role in the regulation of axonal branching of motoneurons [PMID: 21062861]. It has been linked to cancers [PMID: 22675565].

GO terms

Biological Process

GO:0061564 axon development
GO:0009966 regulation of signal transduction

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.