Osteomodulin (IPR030705)

Short name: Osteomodulin

Overlapping homologous superfamilies


Family relationships



Osteomodulin (OMD), also called osteoadherin, belongs to the family of leucine-rich repeat proteins (SLRPs) of the extracellular matrix, which have crucial roles in regulating skeletal homeostasis and development [PMID: 9642227]. Osteoclasts is a type of bone cell that reabsorbs bone tissue. Bone resorption by osteoclasts stimulates bone formation by osteoblasts. The expression of osteomodulin in osteoblasts is induded by osteoclastic activity, indicating that it is involved in bone homeostasis [PMID: 17714690].

GO terms

Biological Process

GO:0030500 regulation of bone mineralization

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0062023 collagen-containing extracellular matrix

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.