Band 4.1-like protein 3 (IPR030691)

Short name: Band4.1-L3

Overlapping homologous superfamilies


Family relationships


Band 4.1-like protein 3, also known as 4.1B or DAL-1, belongs to the protein 4.1 family. Members of the 4.1 family contain a 4.1/ezrin/adixin/moesin (FERM) domain, which is involved in the linkage of cytoplasmic proteins to the membrane [PMID: 9757824].

Protein 4.1B has been described to be a growth suppressor [PMID: 11996670, PMID: 9892180]. It localises to the cell membrane to sites of cell-cell contact, and functions as an adapter protein, linking the plasma membrane to the cytoskeleton [PMID: 9892180, PMID: 25183197]. It is involved in cytoskeleton-associated processes, such as cell motility and adhesion, and also plays a role in the regulation of cell growth, differentiation, and the establishment of epithelial-like cell structures [PMID: 25183197].

GO terms

Biological Process

GO:0007016 cytoskeletal anchoring at plasma membrane
GO:0007010 cytoskeleton organization
GO:0001558 regulation of cell growth

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005911 cell-cell junction
GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.