Peptide/nickel binding protein, MppA-type (IPR030678)

Short name: Peptide/Ni-bd

Overlapping homologous superfamilies


Family relationships


Solute-binding protein family 5 consists of peptide and nickel-binding proteins [PMID: 8336670]. MppA, a member of this family, is essential for import of the bacterial cell wall peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate [PMID: 9495761]. GsiB (YliB) is a glutathione-binding protein [PMID: 16109926]. XP55 from Streptomyces lividans is one additional protein of unknown function that belongs to this group [PMID: 3453116].

Proteins in this entry include:

  • Periplasmic oligopeptide-binding proteins (oppA) of Gram-negative bacteria and homologous lipoproteins in Gram-positive bacteria (oppA, amiA or appA)
  • Periplasmic dipeptide-binding proteins of Escherichia coli (dppA) and Bacillus subtilis (dppE)
  • Periplasmic murein peptide-binding protein of E. coli (mppA)
  • Periplasmic peptide-binding proteins sapA of E. coli, Salmonella typhimurium and Haemophilus influenzae
  • Periplasmic nickel-binding protein (nikA) of E. coli
  • Haem-binding lipoprotein (hbpA or dppA) from H. influenzae
  • Lipoprotein xP55 from Streptomyces lividans
  • Hypothetical proteins from H. influenzae (HI0213) and Rhizobium sp. (strain NGR234) symbiotic plasmid (y4tO and y4wM)

GO terms

Biological Process

GO:0055085 transmembrane transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0043190 ATP-binding cassette (ABC) transporter complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.